Washington DC 2014
From Wednesday November 12 and Thursday November 13 2014, the 2014 CHARGE DC Meeting Organizing Committee (Tamara Harris, Lenore Launer, Christopher O’Donnell, Bruce Psaty) and the CHARGE RSC hosted the CHARGE Investigator meeting at the Embassy Suites Convention Center in Washington, DC.
Christopher J. O'Donnell, MD, MPH NHLBI
Meet the Directors: Harnessing Global and Collaborative Science for Genomics Research for Common Diseases
Gary H. Gibbons, MD NHLBI
Richard J. Hodes, MD NIA
Eric D. Green, MD NHGRI
Errol G. Levy, BSc., MSc., MPP European Union
Genome Commons
Eric Boerwinkle, Ph.D. University of Texas at Houston
Genome Sequencing
Sudha Seshadri, MD., Boston University, "The Alzheimer Disease Sequencing Project Discovering rar risk and protective variants"
Andrew P. Morris, Ph.D. University of Liverpool, "The genetic architcture and pathophysiology of type 2 diabetes: lessons learned from sequencing, genotyping an dhigh-density imputation in the T2D-GENES" (not released)
Working Group Presentations
Renal: Adrienne Tin, Ph.D. Johns Hopkins Bloomberg School of Public Health, "Exome-wide sequencing analysis of kidney function"
Epigenetics: Roby Joehanes, PhD., Institute for Aging, Harvard University, "Meta-analysis of epigenome-wide association studies between DNA methylation and smoking status"
Glycemia-T2D: Shuai Wang, M.S., Boston University, "Gene-based tests with defined functional categories revealed novel findings"
Genomics in Multi-Ethnic Cohorts
Donald W. Bowden, Ph.D., Wake Forest University,"Genetic analysis in populations with non-European ancestry: COGENT, MEDIA and AAGILE"
Chao Agnes Hsiung, Ph.D., National Health Research Instititue in Taiwan, "TIACHI -Taiwan Cohort for Genetic Epidemiologic Studies of Cardiometabolic Disease and its Risk Factors in Chinese"
Cathy C. Laurie, Ph.D., University of Washington, "An Introduction to the Hispanic Community Health Study / Study of Latinos"
Timothy A. Thornton, Ph.D., University of Washington, "Statistical methosds for genetic analysis in admixed poputlations: Applications to the Hispanic Community Health Study / Study of Latinos"
Thursday November 13, 2014
Translational Genomics
Stephen J. Chanock, M.D., National Cancer Insitute, "Genomic studies in cancer cohorts: current directions and collaborative opportunities"
Mark Caufiled, M.D., Genomics England, "100,000 Whole Genomie Sequencing Project"
Steven R. Cummings, M.D., University of California, San Francisco, "Translational Collaborations"
Omics
Thomas J. Baranski, M.D., Ph.D., Washington University at St. Louis, "Drosophila model for functional genomics"
Myriam Fornage, Ph.D., University of Texas at Houston, "Genome-wide DNA methylation studies in the CHARGE Consortium"
Andrew D. Johnson, Ph.D. National Heart, Lung, and Blood Institute, "RNA expression: aging, genetics and beyond"
CHARGE-ENCODE Collaborations
Leonard Lipovich, Ph.D., Wayne State University, "ENCODE-CHARGE Collaboration update: Integration of GWASNPology and LncRNAomics points to long non-coding RNA genes as direct causal candidates in type II diabetes, glycemia, and beyond"
Robert J. Klein, Ph.D., Icahn School of Medicine at Mount Sinai, "CHARGE-ENCODE Collaborations"
Working Group Presenations
CHD: Alanna C. Morrison, Ph.D., University of Texas at Houston, "Novel genes associated with myocardial infarction and coronary heart disease"
JHS: Jin Li, B.S., University of North Carolina, Chapel Hill, "Genome-Wide Admixture and Association Study of Serum Iron, Ferritin, Transferrin Saturation, and Total Iron Binding Capacity in African Americans"
Expression: Marjolein J. Peters, MSc., Erasmus Medical Center, "Identification of cis-and trans-acting variants in RNA sequencing data: a CHARGE-ENCODE collaboration"
CHARGE Golden Tiger Awards
Golden Tiger Awards were (hastily) presented on November 13th to the following CHARGE investigators:
Early Career Achievement:
Sven van der Lee
Bing Yu
Working Group Contributions:
Robi Joehanes (Epigenetics)
Misa Graff, Anne Justice, Thomas Winkler (Adiposity)
Working Group Leadership:
Mark Goodarzi & Robert Scott (Diabetes-Glycemia)
Joanne Murabito (Aging & Longevity + ReproGEN)
Rozenn Lemaitre (Fatty Acids)
CHARGE Leadership:
Myriam Fornage
Susan Heckbert
CHARGE Contributions:
Erika Enright
Ann Walsh
Outstanding Poster:
Frank J. A. van Rooij, “Trans-ethnic meta-analysis of erythrocyte traits”
Lindsay M Reynolds, “Age-related variations in the methylome associated with gene expression in human monocytes and T cells.”