Embassy Suites Downtown: Denver, CO
On behalf of the CHARGE Research Steering Committee and local hosts Leslie Lange and Cheryl Ackert-Bicknell (University of Colorado), we are pleased to provide details for the spring CHARGE Investigator Meeting at the Denver Embassy Suites Downtown Hotel.
The main Congress sessions and most working group meetings will take place Thursday and Friday, May 23 and 24. On Thursday evening, we will hold a poster reception shortly after the main congress session.
All of Us will hold a pre-conference scientific workshop on Wednesday, May 22 in the afternoon; it will be followed-up by a practical session on Friday afternoon, May 24 providing investigators an opportunity for hands-on application. Both sessions are open to all registered conference attendees.
Conference Highlights
May 22
All of Us Scientific Workshop
Insights from the NIH All of Us Research Program - A Comprehensive Journey through Emerging Scientific Findings, Cross-Cohort Analyses, and Genomic Discovery
1:00 to 5:00 pm.
Led by: Josh Denny, All of Us CEO
See below for details
Meet Up
Early evening informal offsite gathering open to all attendees No sign-up required.
May 23 & 24
Invited Congress Session Speakers
The main Congress sessions include talks from invited speakers and oral presentations from highly-rated abstract submissions. The sessions will take place Thursday afternoon and Friday morning, May 23 & 24.
Arjun Krishnan (University of Colorado)
Kathryn Lunetta (Boston University)
Gladys Maestre (University of Texas Rio Grande Valley)
Jonathan Pritchard (Stanford University)
Laura Raffield (University of North Carolina)
Ken Rice (University of Washington)
Barbara Stranger (Northwestern University)
Matthew Taylor (University of Colorado)
André Uitterlinden (Erasmus MC)
See detailed Agenda below
May 23
Working Group Meetings
8:00:
Lipids
Hemostasis
Neurology
9:00:
Polygenic Risk
Monet Multi-Omic Workshop
Neurology
10:00:
CHD/Athero
Gene-Lifestyle
Microbiome
11:00:
Proteomics
Neurology
May 24
All of Us Hands-on Workshop
Genomic research in the All of Us Researcher Workbench
A 2.5 hour session delving into how to utilize genomic data within the All of Us Researcher Workbench. Attendees will be able to actively learn through presenter led hands on activities.
1:30 to 4:00 pm.
Led by: Mary Davis, PhD Associate Professor, Brigham Young University and Megan He, PhD Scientific Research Project Manager, Vanderbilt University Medical Center
See details below, including how to create a Researcher Workbench account.
Housing
Embassy Suites Denver Downtown Reservations
1420 Stout Street, Denver, CO 80202
tel: +1.303.592.1000
The Meeting will take place at the Embassy Suites Denver Downtown Hotel. A limited number of rooms are available at a conference rate: $249.
Please note: The conference rate is available on a first-come first-served basis. Please reserve early as the group block must be booked by April 30 and frequently sells out prior to the deadline. The rate increases on May 1, 2024.
NIH and Government employees should contact chargemt@uw.edu to receive a special government rate registration link.
We ask that you support CHARGE by staying at the conference hotel. Our meeting space pricing is based on attendees booking with the Embassy Suites.
Conference Registration
Meeting Registration is managed by the University of Washington conference services.
Full conference registration: $420
($500 April 27 and after)One-day registration: $250
($300 April 27 and after)
Registration includes lunch, snacks, and coffee on the selected day(s) and Thursday evening’s poster reception.
Agenda
All Times are Tentative
Thursday, May 23
Working Group Meetings Breakout Rooms
8:00: Lipids, Hemostasis, Neurology
9:00: Polygenic Risk, Monet Multi-Omic Workshop, Neurology
10:00: CHD/Athero, Gene-Lifestyle, Microbiome
11:00: Proteomics, Neurology
Lunch Cripple Creek Ballroom
Congress Session Crystal Ballroom 1:00 pm to 5:00 pm
Invited Speakers
André Uitterlinden (Erasmus MC) Genome of Europe project
Laura Raffield (University of North Carolina) Updates from the TOPMed Multi-Omics Working Group
Gladys Maestre (University of Texas Rio Grande Valley) Building infrastructure to assess the pathobiology of health disparities
Kathryn Lunetta (Boston University) Challenges and opportunities working with aging phenotypes
Abstract Talks
Jayna Nicholas (University of North Carolina at Chapel Hill) Cross-Population Comparison of Aptamer and Antibody Proteomics Measures
Daeeun Kim (University of North Carolina at Chapel Hill) The Impact of Long-term Exposure to Air Pollution on Plasma Proteomic and Metabolomic Profiles in UK Biobank
Iain Konigsberg (University of Colorado - Anschutz Medical Campus)Constructing and Evaluating Omic Risk Scores for Chronic Obstructive Pulmonary Disease-Related Traits
Paula Reventun (Johns Hopkins University) RAB5C regulation of VWF secretion
Valborg Gudmundsdottir (Icelandic Heart Association) Serum proteomics reveal APOE-dependent and independent protein signatures in Alzheimer's disease
Poster Blitz: One-minute presentations selected from the meeting’s top-scoring abstracts
Poster Session & Reception Silverton Ballroom, 6:00 - 8:00 pm
Friday, May 24
Congress Session Crystal Ballroom 9:00 am to 12:00 pm
Invited Speakers:
Matthew Taylor (University of Colorado Anschutz Medical Campus) Trans-Omic Analyses in Heart Failure
Jonathan Pritchard (Stanford University) How natural selection shapes what we find in GWAS.
Barbara Stranger (Northwestern University) The role of sex in the genetics and genomics of complex traits in humans
Arjun Krishnan (University of Colorado Anschutz Medical Campus) Advancing data-driven biology to unravel complex disease mechanisms
Ken Rice (University of Washington) How should we visualize heterogeneity in meta-analyses? Have your say!
Abstract Talks
Themistocles Assimes (Stanford University) Contemporary Polygenic Scores of Low-Density Lipoprotein Cholesterol and Coronary Artery Disease Predict Coronary Atherosclerosis in Adolescents and Young Adults
Sarah Urbut (Massachusetts General Hospital) AladynIndividual: Capturing Individual Informed Latent Disease Trajectories across time and genomic profiles
Jennifer A Brody (University of Washington) Evaluating off-target drug effects seen in RCTs using proteomics and Mendelian randomization
Lunch Cripple Creek Ballroom
Workshop Crystal Ballroom 1:30 - 4:00 pm:
Genomic research in the All of Us Researcher Workbench
All of Us Workshop and Workbench Details
Wednesday afternoon, May 22
Insights from the NIH All of Us Research Program - A Comprehensive Journey through Emerging Scientific Findings, Cross-Cohort Analyses, and Genomic Discovery
Genomic and other data are broadly available in the cloud-based platform, the All of Us Researcher Workbench. Here, researchers have discovered >275M previously unreported genetic variants, identified from data shared by nearly 250,000 All of Us participants. This extensive dataset, enriched with non-European genetic ancestry, opens new avenues for understanding genetic influences on health. Join us to delve into the emerging scientific impact and cross-cohort analyses.
This workshop is open to all registered attendees. 1:00 pm to 5:00 pm.
Led by: Josh Denny, All of Us CEO
Speakers:
Josh Denny (All of Us Research, NIH) - Overview of All of Us
Jacob Keaton (Denny Lab) - BP PRS in All of Us
Peter Sauer (Denny Lab) - Clopidogrel & CYP2C19
Henry Taylor (Collins lab) - T2D and OmicsPred PheWAS
Ariel Williams (Denny Lab) - APOL1 risk variants in All of Us
Chenjie Zeng (Denny Lab) - Rare variants/PheRS
Mary Davis (Brigham Young University) - Multiple Sclerosis
Friday afternoon, May 24
Genomic research in the All of Us Researcher Workbench
Join us for a 2.5 hour session delving into how to utilize genomic data within the All of Us Researcher Workbench. Attendees will be able to actively learn through presenter led hands on activities.
This workshop will be most beneficial to data scientists, bioinformaticians, health services researchers, epidemiologists, and genomics researchers at the introductory or intermediate level. It is recommended that attendees have basic familiarity with using R and/or Python programming languages and a working knowledge of basic genetic association study concepts and prior experience running a genetic association analysis. It is recommended that attendees bring a laptop and register with the All of Us Research Program (https://www.researchallofus.org/register/) prior to the start of the workshop to participate in all activities.
This workshop is open to all registered attendees. Tentatively set to run from 1:30 pm to 4:00 pm.
Led by: Mary Davis, PhD Associate Professor, Brigham Young University and Megan He, PhD Scientific Research Project Manager, Vanderbilt University Medical Center
Speakers:
Mary Davis (Brigham Young University) & Megan He (Vanderbilt University Medical Center) – Genomic research in the All of Us Researcher Workbench
Tam Tran (Denny Lab) - Hands-on PheTK Demo
Slavi Goleva (Denny Lab) - Example: working through hypertension drug effectiveness
Transportation Options: Denver Airport to Embassy Suites Downtown Hotel
Denver Airport → Embassy Suites Denver Downtown Hotel Options: (Rome2Rio)
Ground Transportation Options at Denver Airport
Light Rail to Downtown Union Station: The A Line provides travelers easy service from the airport to downtown Denver
Ride App Services: Ride shares can be accessed on Island 5 of either side of the terminal (East or West)
Taxi Services: Rates as well as a list of taxi cabs operating at the Denver Airport
Local Attractions
Urban sophistication meets outdoor adventure in Denver. Get acquainted with The Mile High City, including history, transportation and neighborhood guides. Welcome to Denver where 300 days of sunshine, a thriving cultural scene, diverse neighborhoods and natural beauty combine for the world's most spectacular playground.
Eater Restaurant Guide: The 38 Essential Restaurants in Denver
Arts and Music:
Denver Center for the Performing Arts
Everything from musicals to immersive experiences - May Performances and Tickets
Denver Arts Festival, May 25 & 26
Only in Denver the Denver Area:
Catch a Colorado Rockies baseball game vs. the Philadelphia Phillies at 7:10 pm, Friday, May 24: Tickets
Meow Wolf Denver: Convergence Station
Created by over 350 local and international artists, Convergence Station features four floors of Meow Wolf's most epic art to date, an interactive performance and event venue, and an unforgettable story of multiversal travel through alien worlds. [Often sells out in advance]
Union Station and Surrounding Area
Nice restaurants and shops
Save the Date
CHARGE Rotterdam October 15 - 17, 2024
Respiratory Illnesses
The safety of CHARGE attendees is our top priority.
Please stay home if you are ill.
Masks are optional, and we continue to welcome and encourage masks as an important tool against respiratory illness.